21408: Permission to send an SMS or MMS has not been enabled for the region indicated by the 'To' number

You have attempted to send an SMS or MMS to a region that has not been enabled in your account's Messaging Geo-Permissions settings. These settings exist to help you ensure you only send SMS or MMS to the countries or regions you operate in, and avoid unexpected charges.

Note: To align with evolving regulatory requirements, Twilio has stopped delivering voice, messaging, and email traffic to recipients in Iran starting March 15, 2025

• You have attempted to send an SMS or MMS to a region that has not been enabled in your account's Geo-Permissions settings.

If you wish to send messages to this region, please enable the relevant permissions on your account using the Messaging Geographic Permissions page.